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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
40
Human Site:
Y198
Identified Species:
62.86
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
Y198
P
E
D
K
L
Q
I
Y
R
D
N
F
E
K
A
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
E181
Y
A
D
A
K
L
K
E
E
E
K
R
A
L
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
Y229
P
E
D
K
L
Q
I
Y
R
D
N
F
E
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
Y198
P
E
D
K
L
Q
I
Y
R
D
N
F
E
K
A
Rat
Rattus norvegicus
Q9JJ31
780
90872
Y198
P
E
D
K
L
Q
I
Y
R
D
N
F
E
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
Y197
P
E
D
K
L
Q
I
Y
R
D
N
F
E
K
A
Chicken
Gallus gallus
XP_417163
809
94020
Y227
P
E
D
K
L
Q
I
Y
R
D
N
F
E
K
A
Frog
Xenopus laevis
Q6GPF3
768
88937
Y201
G
L
E
G
R
S
V
Y
E
E
D
F
E
A
P
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
Y198
T
D
D
K
L
Q
I
Y
R
E
N
F
E
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
I196
R
S
L
V
R
D
V
I
E
C
Y
V
E
L
S
Honey Bee
Apis mellifera
XP_623958
789
91733
Y201
A
T
D
K
L
Q
I
Y
R
E
N
F
E
A
A
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
Y183
G
E
D
P
L
L
V
Y
R
Q
S
F
E
R
Q
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
Y213
S
E
D
R
L
Q
I
Y
K
E
N
F
E
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Q184
Y
V
E
I
G
M
G
Q
M
E
R
Y
E
E
D
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
N216
P
Q
D
L
K
K
L
N
L
N
V
Y
I
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
100
100
20
73.3
N.A.
6.6
73.3
46.6
73.3
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
100
100
46.6
93.3
N.A.
20
80
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
0
0
0
0
0
0
0
7
14
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
80
0
0
7
0
0
0
40
7
0
0
0
7
% D
% Glu:
0
54
14
0
0
0
0
7
20
40
0
0
87
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
74
0
0
0
% F
% Gly:
14
0
0
7
7
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
60
7
0
0
0
0
7
0
0
% I
% Lys:
0
0
0
54
14
7
7
0
7
0
7
0
0
54
0
% K
% Leu:
0
7
7
7
67
14
7
0
7
0
0
0
0
14
0
% L
% Met:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
7
60
0
0
0
0
% N
% Pro:
47
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
7
0
0
0
60
0
7
0
7
0
0
0
7
7
% Q
% Arg:
7
0
0
7
14
0
0
0
60
0
7
7
0
7
7
% R
% Ser:
7
7
0
0
0
7
0
0
0
0
7
0
0
0
14
% S
% Thr:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
7
0
0
20
0
0
0
7
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
0
0
0
0
74
0
0
7
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _